A recent study indicates that people who come off popular slimming jabs like Wegovy and Mounjaro tend to recover shed pounds far faster than those who halt conventional diet and exercise regimens.
Findings released in a leading medical journal demonstrates that while obese people can lose substantial amounts of their body weight while on the medication, the weight returns at an average rate of 0.8 kg per month once they quit.
"Users using these treatments need to be aware of the potential of rapid weight regain when the therapy is stopped," stated expert Dr. Susan Jebb.
That rate of recovery suggests a reversion to starting weight in about 18 months.
Analyzing Treatments
The research, which examined dozens of trials involving thousands of patients, contrasted the results of the injectable medications with other pills.
Researchers emphasize that individuals who shed pounds through lifestyle changes alone typically experience a slower weight regain—around 100 grams monthly—post-intervention.
Explaining the Rapid Regain
Doctors suggest the mechanism of the drugs is key to understanding the accelerated rebound.
The injections mimic a natural hormone called glucagon-like peptide-1, which controls appetite.
"Artificially providing the hormone levels several times higher than normal could lead to the system to generate a reduced amount of its own natural GLP-1, and may also reduce responsiveness to its actions," noted Dr. Adam Collins, a dietetics specialist.
"Withdrawal of this medication means hunger is no longer kept in check, making excessive eating much more probable."
A Chronic Disease?
The NHS suggest the jabs for individuals with weight-linked medical conditions, accompanied by prescribed diet and exercise modifications.
Many experts contend that, due to the significant potential of relapse, the therapy might need to be long-term.
This opinion is reinforced by drug manufacturers, who note that the findings "emphasize the persistent character of obesity," similar to managing diseases like high blood pressure.
Patient Experiences
Users who have stopped the jabs describe a powerful resurgence of cravings.
"It was like something that goes on and I was suddenly starving," described a patient.
The struggle is worsened if patients have not developed sustainable lifestyle or habit changes during therapy.
Widespread Use
Figures suggest that millions of people in the UK have tried weight-loss jabs in the past year, with desire remaining high.
- Adoption is more common among women than men.
- The 40s and 50s age group shows the greatest usage rates.
- Many obtain the drugs through private prescriptions rather than public health services.
Ultimately, experts stress that while these medications are effective agents for weight loss, they are not a permanent cure and long-term success hinges on ongoing lifestyle management.
